منابع مشابه
Waltz of the chromosomes
cientists have discovered a new function for amyloid precursor protein (APP), a protein linked to Alzheimer’s disease. The finding may reveal how APP gets mixed up with the enzymes that make it go bad. APP has an evil reputation. The and secretases transform it into amyloidpeptide, a component of the plaques that riddle the brain in Alzheimer’s disease. Previous work by Larry Goldstein (Univesi...
متن کاملChromosomes in the ‘hood
omites, the precursors of vertebrae, striated muscle, and dermis, are laid down in a timed sequence from anterior to posterior. Now, Alexander Aulehla, Bernhard Herrmann (Max-PlanckInstitut für Immunbiologie, Freiburg, Germany), and colleagues report that a gradient and two dueling molecular clocks, all driven directly or indirectly by Wnt3a, combine to create the striped pattern of somites. Th...
متن کاملI-18: The Role of Sex Chromosomes in Female Germ Cell Differentiation
Background When gonadal sex reversal occurs in mammalian species, the resultant XX males and XY females become infertile or subfertile, suggesting critical roles of sex chromosomes in germ cell differentiation. The objective of our study is to clarify the mechanism of infertility in the B6.YTIR (XY) sex-reversed female mouse, which can be attributed to a failure in the second meiotic division i...
متن کاملThe chromosomes of the Filariae
An understanding of the nature of the chromosomes of the filariae is expected to greatly assist the future interpretation of genome data. Filarial development is not eutelic, and there does not seem to be a fixed number of cell divisions in the way that there is in Caenorhabditis. It is not clear whether the chromosomes of the filariae have localized centromeres or whether they are holocentric....
متن کاملThe Chromosomes of Drosophila Pseudoobscura
H E linear arrangement of genes within chromosomes is constant T from generation to generation in each line of descent. The degree of this stability is comparable to that of the gene structure; genes change by mutation, chromosomes change by the occurrence of chromosomal aberrations. Strains and races of the same species, as well as distinct species, may differ in gene arrangement. One of us (S...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature
سال: 1938
ISSN: 0028-0836,1476-4687
DOI: 10.1038/141267c0